Synthesis of Novel 6-(Substituted benzyl)imidazo[2,1-b][1,3]thiazole Catalyzed by Polystyrene-Supported Palladium(II) Ethylenediamine Complex
نویسندگان
چکیده
O complexo etilenodiamina paládio(II) suportado em polímero, [PS-en-Pd(II)], é um catalisador altamente ativo, usado para a reação de acoplamento de Sonogashira entre um iodeto de arila e brometo de 2-amino-3-(2-propinila)1,3-tiazólio, 3. Esse catalisador heterogêneo de paládio é eficiente, estável e reciclável. A reação do composto 3 com vários iodetos de arila, 4a-f, na presença do complexo [PS-en-Pd(II)] leva à produção dos 6-(benzil)imidazo[2,1-b][1,3]tiazóis, 5a-f.
منابع مشابه
Palladium-catalyzed microwave-assisted direct arylation of imidazo[2,1-b]thiazoles with aryl bromides: synthesis and mechanistic study.
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تاریخ انتشار 2009